Recombinant hirudin for unstable angina pectoris. A multicenter, randomized angiographic trial.
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چکیده
منابع مشابه
Recombinant hirudin for unstable angina pectoris. A multicenter, randomized angiographic trial.
BACKGROUND Coronary artery thrombosis plays an important pathophysiological role in unstable angina and non-Q-wave myocardial infarction. To date, heparin and thrombolytic therapy has not provided complete or consistent benefit. We hypothesized that recombinant hirudin, a direct thrombin inhibitor, would prevent accumulation of coronary artery thrombus in a manner superior to heparin. METHODS...
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The clinical, left ventricular and coronary angiographic data, and the technetium-99m stannous pyrophosphate (99mTc-PYP) myocardial scintigraphic results are presented in 31 patients with unstable angina pectoris. One-third of these patients had positive 99mTc-PYP myocardial scintigrams in a pattern suggesting limited and diffuse subendocardial necrosis. The positive 99mTc-PYP myocardial scinti...
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ژورنال
عنوان ژورنال: Circulation
سال: 1994
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.89.4.1557